S4-E42.4 – Hannes Hagström on the Broad Aperture of the SLD Summit

S4-E42.4 - Hannes Hagström on the Broad Aperture of the SLD Summit
The EASL SLD Summit aims at updating a global community of liver stakeholders on the most recent advances in SLD research, both pre-clinically and clinically, focusing on MASLD and tackling the issue of MetALD. In this episode, Jörn Schattenberg, Louise Campbell and Roger Green review the recently concluded meeting with faculty members Sven Francque and Hannes Hagström in two seperate interviews.

This conversation featuring Hannes starts with him discussing a couple of very exciting projects that his lab at the Karolinska Institute is working on now. After which, Roger asks Hannes and Jörn to discuss why the energy in this meeting – especially as the debut SLD Summit – felt more vibrant to them than last year’s NAFLD Summit. Jörn comments that the broader aperture afforded by the new nomenclature led to talks on a wider variety of subjects than in previous years. Hannes notes three new areas of focus: first alcohol, second, problems with biopsy and third, a transition from ordinal variables (or what Hannes describes as the human tendency to categorize everything) to using more of a continuous spectrum to categorize MASH and fibrosis. Jörn notes how important this redefinition of variables is in terms of creating analytical error. The next couple of minutes include a conversation on how to consider MetALD in the context of alcoholic and nonalcoholic liver disease. Jörn then discusses a session at which he spoke on Sunday, a look at new mechanisms of action titled “Beyond the Usual Suspects.”

With that, listen to the full episode to gain a richer understanding than can be described in this summary. If you have questions or comments around the Summit or any other themes addressed in this episode, we kindly ask that you submit reviews wherever you download the discourse. Alternatively, you can write to us directly at questions@SurfingNASH.com.

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