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S4-35.2 - Challenges Associated with Communicating New Nomenclature

S4-35.2 – Challenges Associated with Communicating New Nomenclature

The Surfers (Jörn Schattenberg, Louise Campbell and Roger Green) discuss the big stories thus far for 2023 and share previews of what to expect from the SurfingNASH program in the coming months. This conversation focuses largely on the various challenges associate with adopting and communicating new nomenclature for liver disease.

S4-35.1 - High-Level Recap of Two Key Events for 2023 Thus Far

S4-35.1 – High-Level Recap of Two Key Events for 2023 Thus Far

The Surfers (Jörn Schattenberg, Louise Campbell and Roger Green) discuss the big stories thus far for 2023 and share previews of what to expect from the SurfingNASH program in the coming months. This conversation introduces two topics to expound on which standout amid a year that proves to be rife with rich, new information.

S4-34.6 - From the Vault: Presentation on Efruxifermin in NASH with Fibrosis

S4-34.6 – From the Vault: Presentation on Efruxifermin in NASH with Fibrosis

On the final morning of the 2022 AASLD Liver Meeting, Stephen Harrison, Sven Francque, Jörn Schattenberg, Ian Rowe, Jeff McIntyre and Roger Green discussed their key takeaways and impressions. Stephen leads this conversation From the Vault to highlight his presentation of results from Akero Therapeutics’ Phase 2b HARMONY Study.

S4-34.4 - Pemvidutide and the Importance of the Actual GLP-1-to-Glucagon Impact Ratio

S4-34.4 – Pemvidutide and the Importance of the Actual GLP-1-to-Glucagon Impact Ratio

Stephen Harrison, Mazen Noureddin, Jörn Schattenberg, Louise Campbell and Roger Green unpack compelling drug development stories from this month’s EASL Congress and ADA meetings. This conversation considers results from the Phase 2b study for the dual GLP-1/glucagon agonist pemvidutide, which wanders into the importance of the actual GLP-1-to-glucagon impact ratio, potentially significant safety signals that remain to be fully studied, and the subject of how much lean muscle mass these agents produce.

S4-34.3 - The Increasing Importance of Omics

S4-34.3 – The Increasing Importance of Omics

Stephen Harrison, Mazen Noureddin, Jörn Schattenberg, Louise Campbell and Roger Green unpack compelling drug development stories from this month’s EASL Congress and ADA meetings. This conversation focuses on the increasing importance of omics and potentially powerful weight-loss therapies presented at the ADA meeting. Other major themes in this session include insights on the role of artificial intelligence and epigenetics.

S4-34.2 - Practical and Plausible Notes On Injectables Versus Oral Agents

S4-34.2 – Practical and Plausible Notes On Injectables Versus Oral Agents

Stephen Harrison, Mazen Noureddin, Jörn Schattenberg, Louise Campbell and Roger Green unpack compelling drug development stories from this month’s EASL Congress and ADA meetings. This conversation digs deeper into the FASCINATE-2 interim analysis data at week 26 of the 52-week trial. The discussion develops into practical and plausible considerations in a comparison between injectable and oral agents.

S4-34 - Drug Development Stories from EASL and ADA: Part 2

S4-34 – Drug Development Stories from EASL and ADA: Part 2

Stephen Harrison, Mazen Noureddin, Jörn Schattenberg, Louise Campbell and Roger Green unpack compelling drug development stories from this month’s EASL Congress and ADA meetings. The session explores a range of topics around the subject of drug development, including notes on orals versus injectables, diabetes medications with potential in the NASH space, new clinical trial data, different drug classes and much more.

S4-33.5 - From the Vault: ILC 2022 Looking Back: NASH Is a Complex Disease

S4-33.5 – From the Vault: ILC 2022 Looking Back: NASH Is a Complex Disease

Last year, roughly 5,000 liver community stakeholders gathered in London for the 2022 International Liver Congress (#ILC2022,) the first major hepatology Congress to be held in person since the start of the pandemic (smaller, but very valuable meetings like NASH-TAG, LiverCONNECT and Paris NASH have taken place with an in-person component, but the International Liver Congress and The Liver Meeting have not). This conversation From the Vault revisits still relevant takeaways as the podcast continues its coverage of emerging stories from EASL Congress 2023.

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