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S4-34.5 - GLP-1s and Lean Muscle Loss

S4-34.5 – GLP-1s and Lean Muscle Loss

Stephen Harrison, Mazen Noureddin, Jörn Schattenberg, Louise Campbell and Roger Green unpack compelling drug development stories from this month’s EASL Congress and ADA meetings. This final conversation continues on the subject of evaluating the GLP-1 drug class and its potential impact on lean muscle loss. The final question of Season 4, Episode 34 considers the big picture scope of what has been learned in the last month that might affect research or conceptual thinking going forward.

July 30, 2023
S4-33.4 - More Presentation Insights on Frequency of Testing, NITs and Biopsy

S4-33.4 – More Presentation Insights on Frequency of Testing, NITs and Biopsy

Sven Francque and Ian Rowe join Jörn Schattenberg and Roger Green to discuss critical and/or compelling presentations and insights from the recently concluded EASL Congress in Vienna. This final session focuses on another paper by Vincent Wong which sparks discussion around the plausibility of shifting from biopsy to NITs and the cost effectiveness and frequency of testing.

July 23, 2023
S4-33.2 - Unmet Needs in the Primary Care Setting for Disease Identification

S4-33.2 – Unmet Needs in the Primary Care Setting for Disease Identification

Sven Francque and Ian Rowe join Jörn Schattenberg and Roger Green to discuss the presentations of interest from EASL Congress 2023. In this conversation, Ian points to a presentation on automated FIB-4 score calculation and e-reminders to detect advanced liver disease in patients with type 2 diabetes. The group goes on to explore big picture questions on the topic of disease identification and tease the differences between hepatology and private practices and management of a population-level disease.

July 22, 2023
S4-33.1 - EASL Congress 2023: Focus on New Nomenclature

S4-33.1 – EASL Congress 2023: Focus on New Nomenclature

Sven Francque and Ian Rowe join Jörn Schattenberg and Roger Green to discuss the new NAFLD/NASH nomenclature shared at EASL Congress 2023. The groups outlines what the changes entail and shares practical considerations around how to implement the changes in different settings and with patients.

July 22, 2023
S4-33 - EASL Congress: Nomenclature and More Compelling Presentations

S4-33 – EASL Congress: Nomenclature and More Compelling Presentations

Sven Francque and Ian Rowe join Jörn Schattenberg and Roger Green to discuss critical and/or compelling presentations and insights from the recently concluded EASL Congress in Vienna. The session focuses on new nomenclature and emerging stories around patient identification, NITs, fibrosis resolution and more.

July 19, 2023
S4-32.4 - The Potential of NASH Drugs as Adjuvant Therapy

S4-32.4 – The Potential of NASH Drugs as Adjuvant Therapy

Stephen Harrison and Jörn Schattenberg join Roger Green to digest and discuss key takeaways from the recently concluded EASL Congress 2023 and ADA 83rd Scientific Sessions. This final conversation considers important topics yet to be addressed in the preceding sessions. One of the prevailing themes explored is the potential of NASH drugs as adjuvant therapy.

July 16, 2023
S4-32.3 - Discussing Other Drugs in the Therapeutic Landscape

S4-32.3 – Discussing Other Drugs in the Therapeutic Landscape

Stephen Harrison and Jörn Schattenberg join Roger Green to digest and discuss key takeaways from the recently concluded EASL Congress 2023 and ADA 83rd Scientific Sessions. In this conversation, the group moves on from analysis around resmetirom to discuss other drug classes in the therapeutic landscape.

July 15, 2023
S4-32.2 - Why We Should Develop Deeper Understanding of Liver Volume

S4-32.2 – Why We Should Develop Deeper Understanding of Liver Volume

Stephen Harrison and Jörn Schattenberg join Roger Green to digest and discuss key takeaways from the recently concluded EASL Congress 2023 and ADA 83rd Scientific Sessions. In this conversation, the group continues to unpack fresh data on resmetirom, discuss its safety profile and speculate ideas around how the field could benefit from an improved understanding of liver volume dynamics.

July 15, 2023
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